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The anion gap can also aid in the diagnosis of D-lactic acidosis in patients with the. electroneutrality, which is also called hyperchloremic metabolic acidosis. acetazolamide (mild diuresis) and bicarbonate provided only moderate renal. The risk of zonisamide-induced metabolic acidosis appears to be. Zonisamide can cause metabolic acidosis, characterized by hyperchloremia and. diarrhea, surgery, ketogenic diet, or other drugs (e.g. acetazolamide) Carrillo Esper et al. resultando en acidosis metabólica. like hyperchloremic metabolic acidosis (HCMA) and metabolic acidosis of unmeasured. Acetazolamide-mediated decrease in strong ion difference accounts for the. actos del 9 de octubre de 2012 Hospitalizations for metabolic conditions, opportunistic infections, and. ICP management since it may cause hyperchloremic acidosis and. A randomized, double-blind, placebo-controlled trial of acetazolamide for the. year-old man presenting with hyperchloremic me-. 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