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References: Hyperkalemic periodic paralysis. new/8578-1-11464.phpnew/4335-1-11782.php Alterations in this channel produce flaccid paralysis, arrhythmias, impaired skeletal. correlation and therapeutic rationale in hyperkalemic periodic paralysis. Amiodarone and acetazolamide for the treatment of genetically. ABSTRACT Hypokalemic periodic paralysis is a rare congenital disease. Acetazolamide treatment of hypokalemic paralysis. Engel WK. tornos del músculo: la parálisis periódica con o sin cambios del potasio,miastenia o desordenes miastenicos. Alteration of Ca channels cause muscle dysfunction periodic paralysis with or without. tion in acetazolamide-responsive myotonia congenita, pa- ramyotonia congenita and hyperkalemic periodic paralysis. Palabras clave: parálisis periódica familiar, hipopotasemia. Hypokalemic periodic paralysis is a rare congenital disease. 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