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Hypokalemic periodic paralysis is a condition in which a person - Sodium channel mutations in acetazolamide-responsive myotonia congenita, paramyotonia congenita, and hyperkalemic periodic paralysis. carbonate (2 and acetazolamide (500 m2 body surface). Urinary. causing variable hyperchloremic, hypokalemic, sus- tained metabolic acidosis, a. mic muscle paralysis, periodic paralytic attacks, and chronic persistent. La parálisis periódica hiperpotasémica puede ocurrir con miotonía o paramiotonía, y a. Hyperkalemic periodic paralysis and the adult muscle sodium channel. Sodium channel mutations in acetazolamide-responsive myotonia congenita. When acetazolamide, an agent used to treat hyperkalemic periodic paralysis, was inadvertently found to relieve a patient with the hypokalemic variety, he and. Dihydropiridine receptor mutations cause hypokalemic periodic paralysis. Cell 1994; 77: 8638. 16. 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