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Neurology 1994; 44:1500-1503. 14. "Abnormal levels of K þ associated with skeletal muscle dysfunction are observed in the condition known as acetazolamide-responsive periodic paralysis (PP). new/2357-1-18999.php Parasrampuria J, et al Stability of acetazolamide sodium in 5% dextrose or 0.9%. Acetazolamide treatment of hypokalemic periodic paralysis: prevention of. new/6720-1-21125.php Learn more about Periodic Paralysis Syndrome at Methodist Healthcare. The 2 most common types of periodic paralysis are hypokalemic and hyperkalemic. This data show the remarkable benefit of acetazolamide on permanent weakness of hyperkalemic periodic paralysis in association with the T704M mutation. Periodic hypokalemic familial paralysis (PHFP) is a channel-mediated disease. 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