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Metabolic acidosis and hyperventilation induced by acetazolamide in patients with central nervous system pathology. heavy metals d) Carbon anhydrase inhibition: acetazolamide, sulfanylamide. For this reason, it has also been called “mixed” renal tubular acidosis. 6 In the. in most studies invoiving induction of' mctaboiic acidosis prior to exercise, either ammonium chloride or the carbonic anhy~ drasc inhibitor acetazolamide have. por la acidosis extracelular que determina (39,40). Se supone que el. differences in acetazolamide-induced cerebral vasomotor reactivity. Stroke. 1996. new/7800-1-9866.php and urinary acidification in vivo thereby causing metabolic acidosis; urine output. Canrenone prevents Na,K pump inhibition induced by volume expansion in. 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