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Adicionalmente los individuos presentan cuello corto, trapecio prominente. megalencephaly and frontal bossing, seizures, hyperreflexia and pyramidal signs, ataxia, and hydrocephalus secondary. the RAAS are plausible candidate genes for modifying blood pressure. responsive to acetazolamide (AZM). Lumbar-peritoneal shunt: In cases of chronic increased intracranial pressure. it is eventually drained away by the normal bodily fluid drainage system. Intraperitoneal diversion of the cerebrospinal fluid in cases of hydrocephalus ( review). of cerebrospinal fluid for- mation by carbonic and anhydrase inhibitor (Diamox). Normal pressure hydrocephalus (NPH) is a clinical symptom complex. repeated lumbar punctures in combination with acetazolamide may be. 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