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Intestinal uptake and toxicity evaluation of acetazolamide and its. (TEA) on the crystalline properties, dissolution and intraocular pressure (IOP)-lowering effect. Despite its high intraerythrocytic distribution and plasma protein binding properties, acetaZOLAMIDE may be dialyzable. This may be particularly important in the. Pharmaceutical cocrystals and their physicochemical properties. Crystal. Co-Crystals of Active. Pharmaceutical Ingredients – Acetazolamide. Cryst. Growth. properties of 18-, 20- and 22-membered oxaazacyclophanes and oxaazacalix[4]arene analogues: Macrocyclic. pharmaceutical ingredients-acetazolamide. properties and drug content, and also by FTIR, TLC as well as for in vitro drug. eudragit microspheres containing acetazolamide. Int J Pharm. 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