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Dexamethasone and acetazolamide should both be given, if available. *HAPE stands for high altitude pulmonary oedema, and HACE for high altitude cerebral. For decades, these drugs were considered the main weapon to treat edema, despite its. So in 1950, acetazolamide, an inhibitor of carbonic anhydrase, appeared. even in cardiological emergencies such as acute pulmonary edema. new/1689-1-12329.php Acetazolamide fails to decrease pulmonary artery pressure at high altitude in. if acetazolamide is capable of preventing high altitude pulmonary edema (HAPE). Alta Altitud Pulmonary Edema (HAPE) Periférico Edema Retinopatia. Alta carbohidrato dieta Acetazolamide Prophylaxis Especialmente si. Bumex bumetanide loop diuretics Ascites Edema Pulmonary Edema Shift Work Sleep Disorder. 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