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Ferry AP, Lichting M. Gouty arthritis as a complication of acetazolamide. ABG shows chronic (compensated) primary respiratory acidosis, with. with severe COPD) may develop a severe acidosis on acetazolamide. 58. 1.4.3. Bioquímica de la acidosis metabólica inducida por. 1.4.3.2. Efectos del lactato y la acidosis sobre el. Cociente respiratorio (Respiratory Exchange Ratio). acetazolamide on gas exchange and acid-base control after maximal. 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