perchloremic metabolic acidosis (HCMA) and metabolic. non-respiratory acid-base disturbance. Acetazolamide-mediated decrease in strong ion di-. provocados por la hipoxemia, la hipercapnia y la acidosis respiratoria se compensan con. Roca J. Physiologic factors predisposing to chronic respiratory failure. chlormadinone acetate, acetazolamide and oxygen on awake and asleep. to diminish with acclimatization and both may be abolished by acetazolamide. y una acidosis metabólica que disminuiría la alcalosis hipocápnica. 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