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Acetazolamide hyponatremia 45 Alkalemia TABLE 120-1 CAUSES OF HYPERCHLOREMIC ACIDOSIS TYPE CAUSE Renal with hypokalemia Proximal RTA, type 2 Distal RTA, type 1 Some. RTA. • Distal (Type I): defective distal H+ secretion. 1°,; autoimmune (Sjögren's, RA). nephrocalcinosis. acetazolamide. heavy metals. new/4013-1-21700.php Drugs that increase urine pH include acetazolamide, [.] potassium. acidosis (RTA) or severe infections of the urinary tract with Proteus bacteria. memantine. M:ethanol; U:remia; D:iabetic ketoacidosis; P:araldehyde; I:NH; L:actic acidosis; E:thylene Glycol; S:alicylate. 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