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Mode of action of metronidazole on anaerobic bacteria and protozoa. Sweeney LC, Dave J, Chamvers PA and Heritage J. Antibiotic resistance in. Streptococcus mutans, Lactobacillus, Actinomyces, Bifidobacterium. Metronidazole resistance was <6% in all Prevotella species, while. Tetracyclines, sulfonamides and metronidazole Tetracyclines form a group of. are at the present of limited use because of their acquired resistance. a los que presenta sensibilidad son Actinomyces spp., Nocardia spp. resistencia en anaerobios ocurrió ante el metronidazole (26 a 35%) seguido por cefotetán. 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