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Welcome to the Actos Legal Counsel website, dedicated to bringing justice to you and your family. Actos Increases Bladder Cancer Risk. Actos (pioglitazone) has been linked with an increased risk of bladder cancer. Actos is a popular diabetes drug sold by Takeda Pharmaceuticals, Inc., and it is. The FDA issued an Actos warning about the diabetes drug's link to bladder cancer. Talk to a lawyer to find out more about a lawsuit. They found no statistically significant association between taking Actos and increased risk of bladder cancer. 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