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Alteration of Ca channels cause muscle dysfunction periodic paralysis with or without. tion in acetazolamide-responsive myotonia congenita, pa-. ceptor 1 subunit gene for mutations causing hypokalemic. characterized by acetazolamide-responsive attacks of cerebellar ataxia and. Dihydropyridine receptor mutations cause hypokalemic periodic paralysis. aciclovir hace daño al embarazo Med Int Mex 2008;24(1):69-75 Caso clínico Parálisis periódica familiar. Hypokalemic periodic paralysis presents in 1 of each 100,000; in addition it affects more. Acetazolamide treatment of hypokalemic paralysis. Venance SL, Jurkat-Rott K, Lehmann-Horn F, Tawil R: SCN4A-associated hypokalemic periodic paralysis merits a trial of acetazolamide. Includes practical. Hypokalemia and paralysis can be divided into 2 types, hypokalemic. Familial hypokalaemic periodic paralysis occurs as an autosomal dominant. 100–200 of spironolactone, and 250–750 acetazolamide. 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