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Molecular diagnosis of Acetazolamide-Responsive Congenital Myotonia. tornos del músculo: la parálisis periódica con o sin cambios del potasio,miastenia o desordenes miastenicos. Alteration of Ca channels cause muscle dysfunction periodic paralysis with or without. tion in acetazolamide-responsive myotonia congenita, pa-. ceptor 1 subunit gene for mutations causing hypokalemic. new/1342-1-19766.php Management considerations in hypokalemic periodic paralysis include. However, if the patient has no response with acetazolamide or if. cell carcinoma{;}Hypokalemic periodic paralysis{;}0.01993886888997892. carcinoma{;}Acetazolamide-responsive myotonia{;}0.006924792613077465. characterized by acetazolamide-responsive attacks of cerebellar ataxia and. Dihydropyridine receptor mutations cause hypokalemic periodic paralysis. Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype. Matthews E. MRCP. 1., Portaro S. M.D. 1,2., Ke Q. M.D. 3,5. 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