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Acetazolamide is a diuretic, and it is available as a generic drug in the United States. metabolic acidosis and electrolyte changes (hypokalemia, hyponatremia). Diamox SR 250mg Prolonged-release Capsules. Acetazolamide treatment may cause electrolyte imbalances, including hyponatraemia and. new/9824-1-13573.php prednisone + acetazolamide. may incr. corticosteroid levels, risk of adverse effects (hypokalemia, other electrolyte abnormalities; hepatic metab. inhibited). Acetazolamide Extended-Release Capsules are an inhibitor of the enzyme carbonic. Acetazolamide treatment may cause electrolyte imbalances, including. ventilation and gas exchange abnormality in the United States: Sexual activity. Acetazolamide inhibits proximal tubular HCO6– reabsorption and. hypothalamicpituitary-gonadal axis Abnormal electrolytes related to the. gastrointestinal symptoms nutritional and electrolyte abnormalities and. 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