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NADH refers to NADH dehydrogenase (subunits 1в4, 4L, 5, and 6); CCO refers to cytochrome-c. Numerous indices of alcohol abuse and alcohol- ism had been increasing since World War II. Mecanismo de ação do abacavir Sweden Pharmacogenetics of the alcohol dehydrogenase system. Cost-efectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity. combination containing abacavir lamivudine and zidovudine trizivir. of elimination of abacavir are metabolism by alcohol dehydrogenase. primary routes of elimination of abacavir are metabolism by alcohol dehydrogenase to form the ' carboxylic acid and glucuronyl transferase to. Name abacavir accession number db0106 type small molecule. By alcohol dehydrogenase and glucuronosyltransferase to a 5′-carboxylic acid. for a pharmacokinetic interaction between abacavir and ethanol, as both are metabolized by alcohol dehydrogenase. 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