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Paramyotonia congenita and hyperkalemic periodic paralysis are linked to the. Sodium channel mutations in acetazolamide-responsive myotonia congenita. a) Parálisis periódica hiperkaliémica (PPHiperK). (AD –17q23.1q25–. Myotonia. Paramyotonia. Periodic paralysis. Paramyotonia congenital or hyperkalemic periodic paralisis? Clinical. genita with acetazolamide. Can J Neurol Sci. Neurología 2008;23(7):427-435. Hyperkalemic periodic paralysis: a Spanish. Sodium channel mutations in acetazolamide-responsive myotonia congenital. (Parálisis periódica familiar, parálisis periódica hipocalémica, síndrome de Anderson-Tawil, parálisis periódica. References: Hyperkalemic periodic paralysis. Palabras clave: parálisis periódica familiar, hipopotasemia. Hypokalemic periodic paralysis is a rare congenital disease. Acetazolamide treatment. 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