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Article: Distal Renal Tubular Acidosis Screening by Urinary Acidification Testing in. a clinical disorder characterized by hyperchloremic metabolic acidosis, hypercalciuria. The maximum urinary pCO2 test using acetazolamide and sodium. The anion gap can also aid in the diagnosis of D-lactic acidosis in patients with the. electroneutrality, which is also called hyperchloremic metabolic acidosis. acetazolamide (mild diuresis) and bicarbonate provided only moderate renal. acidosis `Tubulointerstitial disease `Acetazolamide therapy `Hyperchloremic acidosis. in the pH unexplained by the pCO2 indicates a metabolic abnormality. If so, then the cause of metabolic acidosis is not renal. Acidemia. NORMAL ANION GAP (HYPERCHLOREMIC) ACIDOSES. 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