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[.]. acetazolamide cause a mild metabolic acidosis and may stimulate breathing. Abnormal urine pH is a risk factor for specific types of nephrolithiasis. calcium; cell and transport physiology; channel; electrolytes; ion; renal physiology. The use of carbonic anhydrase inhibitors such as acetazolamide. No role exists for acetazolamide to reduce intracranial pressure (DIII). for dose-dependent nephrotoxicity and electrolyte disturbances. are a number of causes for this abnormality including distal renal tubular acidosis, hypokalemia, diets rich in animal protein and or diets low in alkali and certain drugs, such as acetazolamide. Miner Electrolyte Metab 1987; 13: 257-66. Praetorius J. Epithelial pathways in choroid plexus electrolyte transport. Effect of acetazolamide and furosemide on the production and composition of. 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