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[.]. acetazolamide cause a mild metabolic acidosis and may stimulate breathing. Sulfamag magnesium sulfate laxatives minerals and electrolytes miscellaneous. Diamox acetazolamide carbonic anhydrase inhibitor. occurs in patients with mild abnormalities in methotrexate elimination or renal reviewed. In this study we examined the effect of 500 mg of intravenous acetazolamide, after correcting for fluid and electrolyte abnormalities, on the acid-base status of 30. are a number of causes for this abnormality including distal renal tubular acidosis, hypokalemia, diets rich in animal protein and or diets low in alkali and certain drugs, such as acetazolamide. 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