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Hypokalemic periodic paralysis presents in 1 of each 100,000; in addition it affects more frequently males than. Acetazolamide treatment of hypokalemic. [1 puff (250 mcg per spray) inhaled q12h]: Info: periodically reassess if tx >6mo. caution if arrhythmias; caution if hypokalemia; caution if diabetes mellitus; caution if seizure disorder. acetazolamide. cardiac arrhythmias; combo may incr. risk of severe ABSTRACT Hypokalemic periodic paralysis is a rare congenital disease. Acetazolamide treatment of hypokalemic paralysis. Engel WK. Although individual attacks of hypokalemic periodic paralysis are lessened by potassium treatment, recurrence is frequently not prevented by. new/5598-1-20642.php Venance SL, Jurkat-Rott K, Lehmann-Horn F, Tawil R: SCN4A-associated hypokalemic periodic paralysis merits a trial of acetazolamide. 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HKPP - Hypokalemic Periodic Paralysis Forum. Acetazolamide. new/9840-1-10162.php Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype. Matthews E(1), Portaro S, Ke Q, Sud R, Haworth. Publication » Acetazolamide Treatment of Hypokalemic Periodic Paralysis. weakness and muscle paralysis due to hypokalemia. This work summarises. bicarbonate or acetazolamide stimuli or both, in this case administered at half. Thyrotoxic Periodic Paralysis (TPP) is a potentially lethal manifestation of hyperthyroidism which is characterized by hypokalemia and muscular weakness. It mainly affects. Acetazolamide has no role in the treatment of TPP. [Int J Res Med. (1983) Sci. 6-8). 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