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hyperchloremic metabolic acidosis (HCMA) and metabolic acidosis. Acetazolamide-mediated decrease in strong ion difference accounts. Primary distal renal acidosis (dRTA) is characterized by hyperchloremic. levels, as assessed both with and without administration of acetazolamide. This article covers the pathophysiology and causes of hyperchloremic metabolic acidoses, in particular the renal tubular acidoses (RTAs). However, this patient appears to have a hyperchloremic metabolic acidosis as well. Reduction of macular oe- dema by acetazolamide in patients with chronic. was admitted forconfusion, cerebellar ataxia associated with hyperchloremic acidosis. Nous rapportons un cas de salicylisme favorisé par l'acétazolamide. In hyperchloraemic acidosis, the anion-gap is normal (in most cases). 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