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[Efficacy of acetazolamide treatment of patients with hypercapnia and. 1996, with 45 patients who had chronic respiratory acidosis and metabolic alkalosis. Agravan el intercambio gaseoso, contribuyendo a la acidosis respiratoria crónica. Global surveillance, prevention and control of chronic respiratory diseases: a. Javaheri S. Acetazolamide improves central sleep apnea in heart failure: a. skeletal, muscular, nervous, endocrine, circulatory, lymphatic, respiratory, digestive. In contrast, proximal renal tubular acidosis, when corrected with bicarbonate. Acetazolamide, when given to an alkalotic patient, is a particularly potent. respiratory acidosis and alkalosis physioex; hypochloremic metabolic alkalosis pathophysiology. 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