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Rabeprazole-based 3-day and 7-day triple therapy vs. omeprazole-based 7-day. moderate and High-Level Metronidazole resistance in helicobacter pylori. new/1715-1-20630.php La resistencia a claritromicina del 17,7% es similar al 15% publicado este año por Henao y. method to detect metronidazole and clarithromycin resistant Helicobacter pylori. Seven-day PPI triple therapy with levofloxacin is very effective for. Omeprazole + clarithromycin + amoxicillin was used during 7 days versus 10. Moderate and High-Level Metronidazole Resistance in Helicobacter pylori. Metronidazole 70%) was the preferred drug of choice for first line therapy. None of the patients in the study received the recommended 10 to 14 days of. as proton pump inhibitors (PPIs) and increased risk of C difficile infection (6, 7). Maximum dose: 4 g per day. Usual duration of therapy: 7 to 10 days. Comments: -IV metronidazole should be infused over 1 hour. -The first IV maintenance dose. 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