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Effects of acetazolamide administration]. Patients with COFA showed an increase of the renal elimination of Hx, X, VA, TP and radioactivity, which was. Elimination Spironolactone is mainly excreted via its metabolites. spironolactone may help to prevent attacks in people who do not respond to acetazolamide. to eliminate existing calculi and, above all, prevent recurrence by acting on. acetazolamide in the management of cystine and uric acid stones." J. Urol., 113:. Acetazolamide increases bicarbonate excretion in urine, making the blood more. Acetazolamide has been shown to impair CO2 elimination during exercise. How to clean pee out of a mattress - eliminate the odor and stain!. Diuretics - Site of Action in Renal Tubule PCT: mannitol, acetazolamide Loop of Henle:. 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