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Article: Hypercapnic respiratory failure in obesity-hypoventilation syndrome: CO 2 response and acetazolamide treatment effects. Effect of metabolic alkalosis on respiratory function in patients with chronic. A role for acetazolamide in chronic obstructive pulmonary disease. Pathogenesis, consequences, and treatment of metabolic acidosis in chronic. Título: Enfermedad de Parkinson: ciclo alcalosis metabólica-acidosis. metabolic cycle - metabolic acidosis - respiratory alkalosi; treatment with acetazolamide. 58. 1.4.3. Bioquímica de la acidosis metabólica inducida por. 1.4.3.2. Efectos del lactato y la acidosis sobre el. Cociente respiratorio (Respiratory Exchange Ratio). acetazolamide on gas exchange and acid-base control after maximal. ABG shows chronic (compensated) primary respiratory acidosis, with. with severe COPD) may develop a severe acidosis on acetazolamide. 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