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Periodic Paralysis: Safety Comparison of #Keveyis (dichlorphenamide) vs. #Diamox (acetazolamide) (dichlorphenamide) for Primary Hyperkalemic and Hypokalemic Periodic Paralysis - SUBSTRACTION ACETAZOLAMIDE SPECT CO-REGISTERED TO. Article: SUCCESSFUL TREATMENT OF HYPOKALEMIC PERIODIC PARALYSIS. This data show the remarkable benefit of acetazolamide on permanent weakness of hyperkalemic periodic paralysis in association with the. new/8902-1-12051.php new/5697-1-10913.php Learn more about Periodic Paralysis Syndrome at Methodist Healthcare. The 2 most common types of periodic paralysis are hypokalemic and hyperkalemic. Periodic hypokalemic familial paralysis (PHFP) is a channel-mediated disease. Acetazolamide opens the muscular Kca2+ channel: a novel mechanism of. 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