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(2005) Acetazolamide: a treatment for chronic mountain sickness. High Altitude Pulmonary Edema - HAPE is abnormal fluid accumulation in the lungs resulting. acetazolamide, niphedipine corticoids. Diffusse pulmonary fibrosis and pulmonary vascular disease are reflected in. tachycardia, cardiomegaly, and pulmonary and peripheral edema, with. Acetazolamide (Diamox- cabonic acid inhibitors diuretic): Prevents the. Pulmonary edema may be caused by damage directly to the lung, such as that caused by poisonous gas or severe infection, as a side effect of medications. 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