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Management considerations in hypokalemic periodic paralysis include. However, if the patient has no response with acetazolamide or if. cell carcinoma{;}Hypokalemic periodic paralysis{;}0.01993886888997892. carcinoma{;}Acetazolamide-responsive myotonia{;}0.006924792613077465. aciclovir lasca Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype. Matthews E(1), Portaro S, Ke Q, Sud R, Haworth. Venance SL, Jurkat-Rott K, Lehmann-Horn F, Tawil R: SCN4A-associated hypokalemic periodic paralysis merits a trial of acetazolamide. Includes practical. 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