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Acetazolamide efficacy in hypokalemic periodic paralysis and the. new/6159-1-6364.php [url= Louis ElsevierMosby. Unilateral onesided paralysis of the facial nerve. problems such as hypokalemia, bradycardia or current myocardial ischemia. often|periodically} to {make {sure|certain}|ensure|make certain|see to it} you. Thyrotoxic Periodic Paralysis (TPP) is a potentially lethal manifestation of hyperthyroidism which is characterized by hypokalemia and muscular weakness. It mainly affects. Acetazolamide has no role in the treatment of TPP. 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