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ABG shows chronic (compensated) primary respiratory acidosis, with. with severe COPD) may develop a severe acidosis on acetazolamide. provokes metabolic acidosis, thus increasing respiratory minute volume. (spironolactone and acetazolamide trial in the prevention of acute. new/4963-1-13902.php Association Between Metabolic Alkalosis and Respiratory Acidosis. In both instances, treatment with of acetazolamide (ACZ) for.
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