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Abacavir and mycophenolic acid, an inhibitor of inosine mono- phosphate dehydrogenase, have profound and synergistic anti-HIV activity. J Acquir. primary routes of elimination of abacavir are metabolism by alcohol dehydrogenase to form the ' carboxylic acid and glucuronyl transferase to. The pharmacokinetics and safety of single doses of abacavir (600 mg), ZDV (300. and cytosolic alcohol dehydrogenase (20), which indicates that the potential.
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