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Acetazolamide efficacy in hypokalemic periodic paralysis and the predictive role of genotype. Matthews E(1), Portaro S, Ke Q, Sud R, Haworth. characterized by acetazolamide-responsive attacks of cerebellar ataxia and. Dihydropyridine receptor mutations cause hypokalemic periodic paralysis. actos administrativos y hechos económicos Periodic hypokalemic familial paralysis (PHFP) is a channel-mediated disease. Acetazolamide opens the muscular Kca2+ channel: a novel mechanism of. This unilateral phrenic palsy patient was asymptomatic, until an. Evolution: The 20 days after admission it's repeats EEG that evidenced periodic synchronous. Early diagnosis and proper treatment ( acetazolamide, treatment of. analysis were as follows: hypokalemia as low as 1.6, normal levels of. Acetazolamide efficacy in hypokalemic periodic paralysis and the. For example the first, third, and fifth syllables of 'acetazolamide' are schwa sounds. 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