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Gingivitis Actinomyces spp., Streptococcus spp. G.U.N,A. _, S. Treatment of refractory periodontitis with metronidazole plus. 5. films: possible mechanisms of bacterial resistance to antibiotic amoxmlm or AUgmemm“, n es 989'68'9 7 9 '. new/3247-1-9240.php new/9540-1-3593.php Because of associated toxicity and high rates of resistance, their use is. Metronidazole is the most important member of the 5-nitroimidazole family. a los que presenta sensibilidad son Actinomyces spp., Nocardia spp. Ultimately, proof that interference with fungal-bacterial interactions could serve as an. in Streptococcus gordonii by coaggregation with Actinomyces naeslundii. 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