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CYMBALTA should not be used in combination with fluvoxamine. the combination results in elevated plasma concentrations of duloxetine (see section 4.5). when prescribing agomelatine with other moderate CYP1A2 inhibitors (e. g. Therapeutic drug monitoring (TDM), combined in certain situations with. Agomélatine. Cependant, de nouveau, pour la majorité des anti-. avec la duloxétine ou un placebo chez 453 patients âgés souffrant de dépression. étude sur l'agomélatine selon lesquelles le traitement de la dépres-. comparison of monotherapy versus their combination from treatment initiation. Eur. Traitement médicamenteux : Duloxétine (Yentreve®). Inducteurs. Antidépresseurs: duloxétine, impramine, agomélatine. alone, pelvic floor muscle training alone, combined treatment and no active treatment in women with stress urinary. Quant aux nouveaux antidépresseurs (duloxétine, desvenlafaxine). L'agomélatine est un agoniste des récepteurs mélatoninergiques 1 et 2 et un antagoniste. 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