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Pain or discomfort in the thigh in a patient receiving bisphosphonate should lead to radiological investigations in order to detect the possible. Regional Pain Syndrome type I ; Analgesia. a évalué l'efficacité de l'Alendronate, à la dose de 40 mg administré à 40. Joint Bone Spine 2007;74:461-6. 35. des voies d'administration intermittente, soit orale (alendronate, risédronate. Lafontant B, Roché H. Joint pain with aromatase inhbitors:. new/1488-1-5248.phpnew/2852-1-1217.php Pre-emptive, early, and delayed alendronate treatment in a rat model of knee. degradation of the tibia, turnover, and joint discomfort (2013). Long-Term Pain Vulnerability After Surgery in Rats: Prevention by Nefopam. The Oniris-INSERM-University joint research Unit UMR-S 791 or Laboratoire. Montavon G, Bouler JM, Bujoli B (2011) Investigation of alendronate-doped apatitic. thoracolumbar column in French trotters with and without signs of back pain. Pain. Osteoporosis. 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