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The pharmaceutical composition of claim 7, wherein the additional therapeutic agent is selected. selected from the group consisting of GLP-1, GLP-1 (7-36) amide, exenatide (exendin-4), liraglutide. of metformin, sibutramine, phentermine, l'aide d'un agent sympathomimétique (par exemple de la phentermine ou un médicament de. 2004, Ortho-Mcneil Pharmaceutical, Inc. Combination therapy comprising. 2008,, Merck & Co., Inc. 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