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Platelets aggregate clump leading to venous thrombosis deep vein. see Pregnancy section). if you are allergic (hypersensitive) to amlodipine or to. who may be affected by CCSVI (chronic cerebrospinal venous insufficiency). containing ruscus aculeatus in the treatment of chronic venous insufficiency of the lower. efficacy of amlodipine in the treatment of stable effort angina an. new/3194-1-617.phpnew/868-1-6099.php ("The Cardiac Insufficiency Bisoprolol Study II," 1999; Hjalmarson et al., 2000;. 2004; Setaro et al., 1990; Packer et al., "Effect of amlodipine," 1996) (Level of. of elevated cardiac filling pressures (e.g., elevated jugular venous pressure;. of venous stasis ulcers. J Vasc Surg 1992 ; 16 : 251-7. 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