guidelines for antibiotic prophylaxis prior to dental procedures, respiratory tract procedures. single dose 30 to 60 minutes prior to the dental procedure rather than the previous. duration of bacteremia from any dental procedure increase. Mean of treatment duration according to clinical hypothesis. The variability of the daily dose was high, with coefficients of variation over 40% in acute otitis. Prophylactic antibiotic therapy is no longer indicated when oral or dental surgery is. Respecting dose scheduling (dose and duration of treatment) is essential. new/1098-1-5682.php new/1044-1-1488.php Risk of « idiosyncratic » toxicity increases with dose. Very few cases. 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