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J Womens Health (Larchmt). 2005 Sep;14(7):609-16. Relative antidepressant efficacy of venlafaxine and SSRIs: sex-age interactions. Thase ME(1), Entsuah R. It is potentially of great clinical importance if an antidepressant were to be more. Plot of pooled efficacy of venlafaxine compared with other antidepressants. Imipramine, a tricyclic antidepressant was the first to demonstrate its efficacy in carefully. to use either serotonergic antidepressants (SSRIs) or venlafaxine as a. 54, no.3, 1993 pages 119-126, STUART A. MONTGOMERY 'Venlafaxine: A new dimension in antidepressant. 'Comparative efficacy of antidepressants'. Type. *172 - Bourin M. Is it possible to predict the activity of a new antidepressant in animals with. 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