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We tested the effects of agomelatine, duloxetine, and their combination on oxidative stress, Ca2+ influx, mitochondrial depolarization, apoptosis, and caspase. What is the difference between Cymbalta and Agomelatine. Duloxetine (sold under the brand names Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela) is a. The present invention relates to the use of a combination of agomelatine and. fluvoxamine, venlafaxine, duloxetine, dapoxetine, nefazodone. DMT is generally not active orally unless it is combined with a monoamine oxidase inhibitor (MAOI) such as a reversible inhibitor of monoamine. It is also used by itself or in combination with paracetamol (acetaminophen) available in the UK as Paramax, and Australia as. Antidépresseurs Enzymes* (métabolites actifs) Agomélatine CYP1A2. 1,0 0,18 0,27 Duloxétine 12 610-1733 0,5 0,20 0,57 Escitalopram 24 360-960 0,8 0,58 1,54. Therapeutic drug monitoring (TDM), combined in certain situations with. 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