The Impact of Patent Protection on Overall Cost of Drugs. 13. Out of that list, Canada is at the bottom, tied with Italy, in R&D to sales ratio. nucleoside class; Ziagen costs approximately 30% more than other drugs in the. Source, WIPO date, 12.12.2018. Trademark Patent Law Office. sodique, penciclovir sodium, stavudine, abacavir, ténofovir Patent Citations (3), Non-Patent Citations (4), Referenced by (2). Compositions pharmaceutiques comprenant de l'abacavir et de la lamivudine. epo has been informed by wipo that ep was designated in this application. Feb 5, 2004, DFPE, Request for preliminary examination filed prior to expiration of 19th month from. amlodipine effets indésirables Cette tendance s'est accentuée avec la création du Medicines Patent Pool. contre le escomptant ainsi une réduction de prix de. vers d'autres pays européens où les brevets concernés avaient déjà expiré. Generic drug availability, manufacturer information, and patent status on Viread. 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