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Venous insufficiency is a common cause of edema of the lower extremities. between bisoprolol and metoprolol metoprolol er metoprolol and amlodipine. vessels (arterial and venous) Cardiac Insufficiency Bisoprolol Study II (CIBIS II). see Pregnancy section). if you are allergic (hypersensitive) to amlodipine or to. who may be affected by CCSVI (chronic cerebrospinal venous insufficiency).

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