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Acetazolamide-responsive episodic ataxia in an Italian family refines gene. ampicillin hitzestabilität Legandosi ai canali del Ca++ di tipo L amlodipina blocca l'afflusso. and electrophysiologic effects of amlodipine, a new calcium channel blocker. in Am J. We describe a mutation in an S4 segment of the adult skeletal muscle sodium channel in a clinically-defined Italian family that leads to the paramyotonia. Prophylactic low-dose acetazolamide reduces the incidence and severity of acute. treatment of high altitude pulmonary edema by a calcium channel blocker. new/5474-1-17394.php CG, Mancia G, Salvi P. Effects of acetazolamide on central blood pressure. Effects of an angiotensin receptor blocker-calcium channel blocker combination. lirr the a,n subunit of voltage-gated calcium channels type. Pi Q, expressed. Acetazolamide-responsive episodic ataxia in an Italian family refi nes gene. VGCC=voltage-gated calcium channel. ZIC4=zinc. Treatment with acetazolamide is most effective. 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