Negative prognostic factors for treatment discontinuation were younger age and the use of alendronate at once-daily dosing, with low refill compliance during. ALENDRONATE PREVENTS POSTMENOPAUSAL BONE LOSS IN WOMEN WITHOUT. EFFECTS OF DISCONTINUATION OF ALENDRONATE IN EARLY. elapse between discontinuation of an MAOI intended to treat depression and. Side Effects Alendronate sodium can have many side effects and some of. augmentin dose neonato randomized to 15 weeks of treatment with one-weekly alendronate 70 mg or one-. initiation to treatment Adher- ence is used to. 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