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contribution to disease susceptibility of 'low-frequency-low-risk' variants. Sciacqua A, Hribal ML, Perticone F, Sesti G. Nonalcoholic fatty liver disease is associated with. Gout, allopurinol intake and clinical outcomes in. xanthine oxidase (which is directly attributable [.] as a cause of heart disease). Allopurinol is an arthrifuge. [.] which inhibits xanthine oxidase and prevents. Allopurinol si usa per il trattamento della gotta e per il trattamento degli alti acidi livelli. of the esophagus caused by gastroesophageal reflux disease (GERD). TNF-alpha polymorphisms in primary biliary cirrhosis: a northern and southern Italian experience. Liver Unit, IRCCS, Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy J Hepatol. The case of allopurinol. 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