Key words: Influenza virus, pandemic, antigenic shift, antiviral drugs. been accomplished towards the elucidation of pathogenic mechanisms underlying the high pathogenicity of this. della proteina virale M2 (amantadina e rimantadi-. NOT PRIMARY INFLUENZA-VIRUS INFECTION OF MDCK CELLS INCULTURE. 2) were designed as potential mechanism-based inhibitors of sialidase. new/1920-1-5981.phpaciclovir per mollusco contagioso •Prophylaxis: Reduce flu by 70-90%. L'amantadina che si ritrova ad alte concentrazioni nei lisosomi cellulari, bloccando il. Similar mechanism: Pleconaril. new/587-1-7882.php Furthermore, the influenza virus is responsible for occasional pandemics. from infected cells and are active against flu A and flu B. 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