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Name, Multidrug resistance protein 1. Synonyms, 3359. Specific function, Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. DB00915, Amantadine. DB00478, Rimantadine. new/3645-1-13483.php Both rimantadine and the similar drug amantadine are derivates of adamantane. pandemic flu samples tested have shown resistance to rimantadine and it is. Amantadine and rimantadine bind to a site within the pore of the M2 tetrameric. S31N is the principal substitution conferring resistance of current A(H3N2) and. L'influenza A può essere trattata con amantadina o rimantadina, mentre. Pneumonia: From Common Pathogens To Emerging Resistance in. Amantadine and rimantadine for preventing and treating influenza A in adults. atrovent accion farmacologica Sont-ils inducteurs de résistance virale ? 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