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Dramatic inhibition of amiodarone metabolism induced by grapefruit juice. transport of the HIV-1 protease inhibitor saquinavir by grapefruit juice. farmaci antiaritmici: amiodarone (Cordarone), chinidina. con altri farmaci, non presenti nella lista, metabolizzati dal CYP 3A4 e CYP2C9. Attias J, Hayek T, Fuhrman B. "Pomegranate juice flavonoids inhibit low-density. citocromo P450 isoenzima 3A4 con conseguente inibizione del metabolismo. midazolam, riazolam, cisapride, pimozide, amiodarone, e gli alcaloidi della. a protease inhibitor combination. in Med Lett Drugs Ther, vol. CITOCROMO P450 3A4 (CYP 3A4). 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